Effects of ecigarettes and vaping devices on cardiac and pulmonary physiology Tsai 2020 The Journal of Physiology Wiley Online Library Electronic Nicotine Delivery Systems (ENDS), including e cigarettes and vapes, are often perceived as a safer alternative to traditional tobacco. But is the evidence really supporting this belief? A recent umbrella review published Vapes aren't just harmless mist or vaporthey can contain addictive nicotine and chemicals that can harm your lungs, brain, and overall health. Knowing the facts = making informed choices. It's important to Health effects and known pathology associated with the use of E cigarettes ScienceDirect