Nicotine Vapes: the Chemicals They Contain, What They Can Do to You Business Insider What's actually inside that vape? Vaping devices don't just deliver flavor or a quick escapethey introduce a mix of chemicals, metals, and addictive substances into the body. Many believe they're just harmless Nicotine, propylene glycol, sweet flavorings, and various toxic chemicals like carcinogens and heavy metals are found in vape juice, posing health risks, especially to youth. Vape Juice & E Liquid Ingredients List (4 Main Components)